Lionel Messi became Barca's record appearance maker in the competition with 76 Copa matches.
Sevilla last week lost a crucial game 1-0 at home to Valencia, who are fifth, but fared better this time as Mesa gave them the lead with an exquisite first-time finish into the far top corner in the 41st minute.
Having headed into the match tied on 47 league goals with West Ham's former stalwart Paolo Di Canio, Antonio was delighted to have surpassed the Italian as he celebrated by lifting a cardboard cut-out of himself at the side of the pitch.
Images from Thursday's action in the Europa League Europa League - Round of 16 Second Leg - matches.
Images from football matches played across Europe.
Barcelona have emerged as favourites to be crowned champions after one defeat in their last 22 Liga games.
A sloppy Real Madrid were held 0-0 at home to Real Betis on Saturday in a further blow to their hopes of retaining the La Liga title.
Former Bayern Munich coach Flick takes over Germany to 2024
Cristiano Ronaldo marked his 600th league appearance with his 20th Serie A goal of the season as Juventus beat Spezia 3-0 on Tuesday to move within three points of second-placed AC Milan.
Ajax forward Quincy Promes got into a fight with one of his relatives there and stabbed him.
Zidane ruled out following in the footsteps of Alex Ferguson, who spent 26 years in charge of Manchester United.
During his visit to Kannur, the stadium in which Maradona participated in an event had witnessed a sea of people
Prime Minister Narendra Modi expressed grief at the passing away of the Argentine legend.
"Football and the world of sports has lost one of its greatest players today. Rest in Peace Diego Maradona! You shall be missed," Tendulkar tweeted.
Striker Mariano's header was glanced onto the crossbar by Sociedad's Andoni Gorosabel while the loose ball fell to Marco Asensio, whose shot was deflected wide for a corner from which Raphael Varane header hit the top of the bar.
Images from UEFA Europa League semi-finals played on Thursday.
Real Madrid forwards Marco Asensio and Karim Benzema struck to give their side a 2-0 win at home to Eibar in La Liga
Bruno Fernandes and Edinson Cavani scored twice each as Manchester United took a giant step towards the Europa League final with a 6-2 drubbing of AS Roma in their semi-final first leg at Old Trafford on Thursday.
Chelsea, Manchester City and Manchester United enjoyed comfortable wins in the English Premier League on Saturday as fans returned to stadiums after an eight-month absence.
Everton's Abdoulaye Doucoure scored an extra-time winner as they edged Rotherham United 2-1 in an absorbing FA Cup
Barcelona coach Ronald Koeman has defended centre-back Gerard Pique's right to make comments about referees favouring Real Madrid.
Real were smarting from a surprise 1-1 draw at struggling Elche in their last match and were missing captain Sergio Ramos, who was out with a stomach bug.
Real have three days to recover from the humbling defeat before Saturday's crunch local derby against Atletico Madrid
New Barcelona signing Sergino Dest said he "followed his heart" by turning down a move to European Champions Bayern Munich in favour of the Catalan side.
Real Madrid were made to toil by the 10 men of Athletic Bilbao but eventually won 3-1 on Tuesday thanks to two strikes from Karim Benzema to go level on points with La Liga leaders Real Sociedad.
Bayern Munich slumped to a shock 4-1 loss at Hoffenheim in the Bundesliga on Sunday. The defeat ended their 32-match unbeaten run in all competitions stretching back to last year.
A summary of Saturday's action in Serie A and La Liga.
The Bavarians, unbeaten now in 32 consecutive matches, also won the domestic league and Cup double as well as the Champions League after Flick took over last November. Their last defeat dates back to December, 2019.
Ivan Rakitic an integral part of the Croatia side who reached the World Cup final in Russia before losing 4-2 to France.
Gareth Bale returns to his former club on a one-year loan deal, with British media reporting that Tottenham Hotspur will pay 20 million pounds ($25.8 million) in wages and fees for the 31-year-old Wales forward.
IMAGES from Champions League matches played on Wednesday.
Argentina's two iconic players may be contrasting characters but they shared many traits
Real also have an outstanding defence, conceding only 25 times last year, and are well covered in every position.
Images from La Liga matches played on Saturday.
Arsenal enjoyed a 3-0 win in Azerbaijan against Qarabag in the Europa League on Thursday and AC Milan beat Greece's Olympiakos Piraeus 3-1 but Sevilla suffered a shock defeat by Russians Krasnodar.
Real Madrid produced a gutsy performance to earn a 1-0 win at Sevilla, on Sunday, which took them level on points at the top of La Liga
Olympique de Marseille were the fall guys on a hectic opening night of Europa League group stage action as German club Eintracht Frankfurt returned from the south of France with a surprise 2-1 victory on Thursday.
Lionel Messi scored a 50th freekick goal for Barcelona as he led his side to a quick-fire comeback to win 3-2 at Valencia on Sunday and keep the pressure on La Liga title rivals Atletico Madrid and Real Madrid.
Images from Sunday's action in La Liga and Ligue 1.
Moroccan Yassine Bono denied Marcus Rashford, Bruno Fernandes, Mason Greenwood and Anthony Martial in either half of the match to keep the match alive
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